RNA machine learning for human health

The Yu lab is dedicated to applying and developing computational biology methods to understand dynamical RNA regulation in human disease systems.

Interests

The Yu lab is particularly interested in questions during RNA synthesis.

RNA structure

RNA splicing

Cleavage and polyadenylation

Effects of drugs

Molecular basis of disease

Therapeutic design

Toolkit

The Yu lab uses both experimental and computational tools to solve questions in RNA biology and aims to improve human health.

High-throughput assays

  • Screen effects on RNA regulation
  • Generate data for modeling
  • Address hypotheses in one experiment

Computational Biology

  • Machine learning
  • Artificial Intelligence
  • Explainability